HACARUS and Shimizu Corporation Exhibit New AI Systems at BioJapan 2022

HACARUS And Shimizu Corporation Exhibit New AI Systems At BioJapan 2022

In collaboration with Shimizu Corporation, HACARUS will exhibit new AI software to detect foreign matter in cultured cells and an automatic calculation system for cell occupancy rate. 

October 11, 2022- Kyoto, Japan- HACARUS INC, the leading provider of big insights from small data, announced with Shimizu Corporation it will exhibit a foreign object detection system for quality control of cell products and a system to calculate cell proliferation rate at BioJapan 2022. 

“Expectations for regenerative medicine continue to rise in Japan and abroad. We will contribute to regenerative medicine through the newly developed system by helping improve cultured cells’ quality and mass production,” said Kenshin Fujiwara, CEO at HACARUS. 

In regenerative medicine, AI is becoming increasingly important in supporting human judgment. Generally, the final inspection to sort out defective cell products containing foreign matter is usually done visually, which may lead to quality inconsistencies. The newly developed detection system detects foreign matter in plastic storage bags containing cultured cells consisting of a sample photographing device (HACARUS Check) and AI (HACARUS AI CORE). HACARUS’ snapped a sample containing foreign matter with the sample camera and adjusted the AI ​​so that the foreign matter could be detected. As a result, the firm could catch all foreign substances in the sample at the verification stage.

Automation of foreign material detection is expected to save human resources and speed up inspections.

When cells grow and reach a specific cell occupancy, they are replanted into multiple containers for “passaging.” If the passaging process is not carried out at the appropriate time, there is a high possibility that the cells will be negatively affected.

Workers observe cell proliferation under a microscope daily to determine cell occupancy. However, since the determination is based on individual sensory and empirical values, the cell occupancy rate is subject to variation. This system automatically calculates cell occupancy rates using AI, enabling stable cell occupancy rate determination. Furthermore, stabilizing the timing of passage is expected to stabilize cell culture by allowing passaging at a constant cell occupancy rate.

The “cell occupancy rate” is the ratio of the area of cells in culture to the total culture surface (blue cells in the photo below).

If you are interested in learning more about our joint venture, please feel free to stop by booth D-15. 

Exhibition Information

Dates: October 12 (Wed.) – 14 (Fri.), 2022 / 10:00 – 17:00 

Venue: Pacifico Yokohama, Exhibition Hall (1-1-1 Minato Mirai, Nishi-ku, Yokohama) 

Booth number: D-15 

Venue Map (Entire PDF): (Japanese only)




HACARUS INC. provides big insights from small data and has since its founding in 2014 supplied solutions in 100+ AI projects across the Medical and Manufacturing fields. Headquartered in Kyoto, Japan, and backed by Osaka Gas and Miyako Capital (Kyoto University) among others, its technology enables humans to make better, faster, and more reliable decisions, based on data-driven insights. HACARUS’ proprietary AI engine is built using Sparse Modeling, a method that understands data like a human would – by its unique key features and is far more resource, time, and energy-efficient when compared to Deep Learning. To learn more, visit https://hacarus.com


About Shimizu Corporation

Shimizu Corporation was founded in 1804. The company began when Kisuke Shimizu I, who was a carpenter in Etchu or what is now Toyama Prefecture, launched the business in the Kanda Kajicho district of Edo (now Tokyo). From the moment the company was founded, Kisuke Shimizu I aspired to wholeheartedly devote himself to the company’s work and create quality reliable structures. Today, Shimizu continually delves deeply into knowledge and technology to meet the needs of its clients and, by extension, society. To learn more, visit https://www.shimz.co.jp/en/

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